Welcome to Bioorganic Chemistry at the Lichtenecker Group
We are a research team working at the interface of organic chemistry, chemical biology, and structural biology. Our research focuses on developing small molecules as innovative tools to investigate complex biological systems.
A major area of our work is dedicated to the design and synthesis of 13C-, 15N-, and 2H-labeled amino acids or metabolic amino acid precursors for different protein overexpression systems. These compounds enable the production of proteins with tailored isotope-labeling patterns, providing powerful probes for biomolecular NMR spectroscopy and advancing the structural and functional analysis of proteins.
If you are interested in our research or would like to discuss potential collaborations, we welcome you to contact us at roman.lichtenecker@univie.ac.at.
In addition to our research activities, we are committed to teaching at the University of Vienna. We currently offer five lecture courses and two seminars each year, covering a broad range of topics in chemistry. We also supervise laboratory and research courses providing students with hands-on experience in modern synthetic chemistry, isotope labeling, and chemical biology.
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Statistics
- > 2000 Students enrolled in our courses (WS25 and SS26)
- > 20 Publications in peer reviewed journals since 2020
- > 10 Collaboration partners worldwide
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Latest degrees
- Alisa Wimmer (Master 03/2026)
- Ines Trettler (Master 12/2025)
- Michael Pfeiffer (Bachelor 12/2025)
- Katharina Schwarz (Bachelor 09/2025)
- Giorgia Toscano (PhD 07/2025)
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Latest publications
- Magn. Reson. 2026, 7, 1, 29-36
- Protein Sci. 2026, 35, 4, e70515
- Org. Process Res. Dev. 2026, doi.org/10.1021/acs.oprd.5c00523
- J. Mol. Biol. 2025, 437, 169465
- J. Mol. Biol. 2025, 437, 23,169379
- J. Mol. Biol. 2025, 437, 23, 169347
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Recent project participations
- AlloSpace. The emergence and mechanisms of allostery. (P. Schanda/FWF 10.55776/I5812, 2022-2026) with P. Schanda (ISTA), D. Madern (Grenoble), C. Brochier-Armanet (Lyon), F. Sterpone (Paris)…
- CD Laboratory for High-Content Structural Biology and Biotechnology. (R. Konrat/Christian Doppler; 2017-2025) with R. Konrat (UniVie) and Boehringer-Ingelheim
Upcoming Conference
We will participate in the 31st International Conference of Magnetic Resonance in Biological Systems (23-27.8.2026 in Davos, Switzerland).